Methods for assessing platelet function
OwnerJonathan Gibbins, Christopher Jones +3inventors
InventorsJonathan Gibbins, Christopher Jones, Alex Bye, Joanne Dunster, Neline Kriek
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OwnerJonathan Gibbins, Christopher Jones +3inventors
InventorsJonathan Gibbins, Christopher Jones, Alex Bye, Joanne Dunster, Neline Kriek
Estimating the term…
The present application relates generally to methods for assessing platelet function, for example in a sample from a subject. These methods can be used to identify subjects based on their platelet reactivity or sensitivity to a platelet activating substance, such as collagen-related peptide (CRP), or a thrombin, ADP, thromboxane A2 or adrenaline receptor agonist. The application also provides methods that involve assessing the level of CD36 in platelets of a subject, the level of GPVI in platelets of the subject, and/or the age of the subject as indicators of the platelet function in that subject. The methods can be used to predict the responsiveness of a subject to anti-platelet therapy and so can form part of a therapeutic method.
A method of assessing platelet reactivity or sensitivity to a platelet activating substance in a sample comprising platelets from a subject, the method comprising:
An anti-platelet therapy for use in a method of treating a subject in need thereof, wherein the subject has:
Dependencies are inferred from the claim text.