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US 2026/0276644 A1Published application
Mass spectrometric analysis
AssigneeElectrophoretics Limited
InventorsIan PIKE, Karsten KUHN
Life of this patent
Estimating the term…
Abstract
Isotopic mass tags for labelling peptides and other biomolecules are provided as well as methods of detecting an analyte by identifying by mass spectrometry one or more of the mass labels or combinations thereof.
Claims17
A set of two or more isotopic mass labels, wherein each label comprises the formula:
- wherein:
- X is a coding moiety having an exact mass,
- L is a bond optionally cleavable by collision in a mass spectrometer,
- M is a mass modifier,
- Re is a reactive functionality for attaching the mass label to an analyte or the analyte, and
- wherein X comprises the following general formula:
3 more elements
A set of two or more isotopic mass labels, wherein each mass label comprises the formula:
- wherein:
- X is a coding moiety having an exact mass,
- L is a bond optionally cleavable by collision in a mass spectrometer,
- M is a mass modifier, and
- A is the analyte, and
- wherein each mass label in the set has a different integer mass, and X comprises the following general formula:
3 more elements
Dependencies are inferred from the claim text.