Paper based microchip electrophoresis for molecular diagnostic tests

Abstract

Embodiments of the present disclosure pertain to methods of separating nucleic acids from a sample by applying the sample to a fiber-based electrophoresis medium and generating an electric field across the fiber-based electrophoresis medium, where the generated electric field induces migration and separation of the nucleic acids across the fiber-based electrophoresis medium. The methods of the present disclosure may also include a step of detecting one or more of the separated nucleic acids on the fiber-based electrophoresis medium, diagnosing a disease or condition based on the detecting, and implementing a treatment decision based on the diagnosis. Additional embodiments of the present disclosure pertain to nucleic acid separation systems for separating nucleic acids and methods of making them.

Dependencies are inferred from the claim text.