Systems and Methods for Processing Tissue
AssigneeAnnoviant, Inc.
InventorsNarendra R. Vyavahare, Teodor Dan Simionescu, Agnes Nagy-Mehesz, Ajay Houde
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Abstract
Embodiments of the present specification provide systems and methods for holding one or more tissues, such as veins, such that the tissue remains open in a chamber while undergoing orbital shaking with various solutions and to allow uniform treatment during a decellularization process. A frame is held on a stand to which the tissues are attached and comprises a tension inducing mechanism to cause the tissues to controllably stretch. The frame is removed from the stand, with the tissue attached to it, and placed in a decellularization chamber for uniform treatment of the tissue.
Claims20
A processing device adapted to decellularize one or more pieces of biological tissue, comprising:
- a frame configured to hold the one or more pieces of biological tissue;
- a first holder configured to atraumatically attach to a periphery of one open end of at least one of the one or more pieces of biological tissue;
- a second holder configured to atraumatically attach to a periphery of an opposing open end of the at least one of the one or more pieces of biological tissue;
- a first member configured to attach the first holder to the frame;
- and
- a second member configured to attach the second holder to the frame, wherein at least one of the first member or second member is configured to lengthen or contract so as to apply tension to the at least one of the one or more pieces of biological tissue.
Dependencies are inferred from the claim text.