Diagnostic device and method
AssigneePola Goldberg Oppenheimer
InventorsPola Goldberg Oppenheimer, Jonathan Rickard, Emma Buchan
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Abstract
A lab-on-a-chip (LoC) (1) comprising a plurality of sampling wells (51, 41) and a nano-porous filter (45). A first sampling well (51) in fluid communication with a second sampling well (41) via a flow path. The nano-porous filter (45) being provided in the first sampling well (51).
Claims21
A lab-on-a-chip (LoC), the LoC comprising a plurality of sampling wells and a nano-porous filter;
- wherein a first sampling well is in fluid communication with a second sampling well via a flow path,
- wherein the nano-porous filter is provided in the first sampling well.
(canceled)
An LoC according to any preceding claim wherein each sampling well is configured to isolate and trap one or more species of extracellular vesicles.
A method of separating extracellular vesicles utilising a lab-on-a-chip (LoC) according to any preceding claim, the method comprising:
- applying a biofluid sample comprising extracellular vesicles to a start point of the flow path;
- the biofluid sample being drawn though each sampling well sequentially;
- the extracellular vesicles being separated by the one or more filters into a plurality of subclasses determined by their size, each subclass being isolated in a separate sampling well.
Dependencies are inferred from the claim text.