Focused ultrasound stimulation for renal denervation
AssigneeMedtronic Ireland Manufacturing Unlimited Company
InventorsBinit Panda, Gerry O. McCaffrey
Life of this patent
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Abstract
Systems and methods of performing a therapeutic procedure by applying a first focused ultrasound (FUS) stimulation energy to a blood vessel wall, observing a patient parameter in response to the first stimulation energy, applying a therapy to the blood vessel wall, applying a second FUS stimulation energy to the blood vessel, observing the patient parameter in response to the second FUS stimulation energy, and determining whether the therapy has been successful based on the observed patient parameter in response to the second FUS stimulation energy.
Claims21
1-15. (canceled)
A method of performing a therapeutic procedure, comprising:
- applying a first focused ultrasound (FUS) stimulation energy to tissue in or proximate a blood vessel wall;
- observing a patient parameter in response to the first stimulation energy;
- applying a therapy to the blood vessel wall;
- applying a second FUS stimulation energy to the blood vessel wall;
- observing the patient parameter in response to the second FUS stimulation energy;
- and
- determining whether the therapy has been successful based on the observed patient parameter in response to the second FUS stimulation energy.
A system for denervation of nerves of a blood vessel comprising:
- a catheter configured for navigation within a blood vessel of a patient;
- at least one energy element formed on a distal portion of the catheter;
- a sensor configured to measure one or more patient parameters operably connected to the catheter;
- a focused ultrasound (FUS) stimulation energy source operably connected to the catheter;
- a therapeutic energy source configured to apply therapy to the blood vessel;
- and
- a computing device including a memory and a processor and storing thereon instructions that when executed cause the computing device to:
- cause the FUS stimulation energy source to generate a first FUS stimulation energy for application to a blood vessel wall via the at least one energy element;
- cause the sensor to sense a first change in a patient parameter as a result of the application of the first FUS stimulation energy to the blood vessel wall;
- cause the therapeutic energy source to generate a therapeutic energy for application to or proximate the blood vessel;
- cause the FUS stimulation energy source to generate a second FUS stimulation energy for application to the blood vessel wall via the at least one energy elements;
- cause the sensor to sense a second change in the patient parameter as result of the application of the second FUS stimulation energy to the blood vessel wall;
- and
- determine whether the therapy has been successful based on the sensed second change in the patient parameter in response to the second FUS stimulation energy.
Dependencies are inferred from the claim text.