Microneedles And Related Methods

A microneedle, comprising:

• a base disposed at a proximal end of the microneedle;
• a tip disposed at a distal end of the microneedle,
• the tip extending along a tip longitudinal axis;
• a shaft disposed between the base and the tip,
• the shaft extending distally from the base along a shaft longitudinal axis;
• at least one lumen defining a channel providing fluid communication within at least the shaft of the microneedle;
• an opening defined at the distal end of the lumen and at a loci on the shaft,
• wherein the opening is optionally offset from the tip longitudinal axis;
• and
• at least one extension extending from the base,
• the at least one extension configured to contact a tissue into which the tip is inserted, the at least one extension comprising at least one of a wing and a collar.

A microneedle, comprising:

• a base disposed at a proximal end of the microneedle;
• a tip disposed at a distal end of the microneedle,
• the tip extending along a tip longitudinal axis,
• a shaft disposed between the base and the tip,
• wherein the shaft defines at least one edge extending distally toward and to the tip, the at least one edge being serrated;
• optionally, at least one lumen defining a channel providing fluid communication within at least the shaft of the microneedle;
• and
• optionally, an opening defined at the distal end of the lumen and at a loci on the shaft,
• wherein the opening is optionally offset from the tip longitudinal axis.

A microneedle, comprising:

• a base disposed at a proximal end of the microneedle;
• a tip disposed at a distal end of the microneedle,
• the tip extending along a tip longitudinal axis,
• the base having a width greater than the width of the tip;
• a shaft disposed between the base and the tip,
• the shaft extending distally from the base along a shaft longitudinal axis,
• wherein the shaft defines a profile that deviates from the shaft longitudinal axis, the shaft optionally defining at least one of a curved profile and an angled profile, and
• the tip optionally being offset from the shaft longitudinal axis;
• at least one lumen defining a channel providing fluid communication within at least the shaft of the microneedle;
• an opening defined at the distal end of the lumen and at a loci on the shaft,
• wherein the opening is optionally offset from the tip longitudinal axis.

A microneedle, comprising:

• a base disposed at a proximal end of the microneedle;
• a tip disposed at a distal end of the microneedle,
• the tip extending along a tip longitudinal axis, the base having a width greater than the width of the tip;
• a shaft disposed between the base and the tip, the shaft extending distally from the base along a shaft longitudinal axis,
• the tip optionally being offset from the shaft longitudinal axis;
• at least one lumen defining a channel providing fluid communication within at least the shaft of the microneedle;
• an opening defined at the distal end of the lumen and at a loci on the shaft,
• wherein the opening is optionally offset from the tip longitudinal axis;
• and
• a plurality of wings extending outwardly from the base,
• the plurality of wings being configured to contact a tissue into which the tip is inserted, at least one of the plurality of wings lying perpendicular to a plane in which the shaft longitudinal axis and the tip longitudinal axis lie.