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US 2026/0273153 A1Published application
System and method for controlling oxygen-enrichment therapy based on microvascular resistance feedback
AssigneeZoll Circulation, Inc.
InventorsJeffrey Lance Creech, Stephen Elwood Myrick, Richard A. Helkowski, Fred Shen, Ramu Perumal, Gary A. Freeman
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Abstract
The present disclosure provides systems and methods for controlling gas-enrichment, e.g., oxygen-enrichment, therapy. One or more sensors and/or one or more imaging systems may be used to measure or determine one or more physiological parameters of the patient. Feedback regarding one or more physiological parameters or microvascular resistance may be provided for titrating or controlling the gas-enrichment therapy.
Claims20
A system comprising:
- a gas-enrichment system configured to enrich a liquid with gas to form a gas-enriched liquid;
- a pump configured to pump the gas-enriched liquid from the gas-enrichment system to a vasculature of a patient;
- one or more sensors configured to measure a blood pressure in the vasculature of the patient, a flow rate in the vasculature of the patient, or both a blood pressure and a flow rate in the vasculature of the patient;
- and
- a controller comprising a processor, a memory, and associated circuitry communicatively coupled to the one or more sensors, wherein the processor is configured to perform operations comprising:
- receiving one or more signals from the one or more sensors, the one or more signals representing a measured blood pressure, a measured flow rate, or both the measured blood pressure and the measured flow rate;
- estimating, based on the measured blood pressure, the measured flow rate, or both the measured blood pressure and the measured flow rate, a microvascular resistance in the vasculature of the patient;
- and
- generating, based on the estimated microvascular resistance in the vasculature of the patient, an alert or a control signal for controlling an amount of the gas-enriched liquid delivered to the patient.
6 more elements
Dependencies are inferred from the claim text.