Use of acrylic acid-containing polymers for molecular imaging of target proteins

Abstract

Acrylic acid-containing polymers that can be used as MRI agents, and condensation reactions for producing same is described herein. Condensation reactions can be used to attach a number of MRI signal-generating molecules and targeting molecules to the polymer, wherein the targeting molecule binds a molecular target of interest such as a cancer biomarker. Advantageously, the acrylic acid-containing polymers provide multiple attachment sites for the MRI signal-generating molecule, enabling an increase in the number of less toxic and less immunogenic MRI signal-generating molecules to detectable levels.

Dependencies are inferred from the claim text.