Compositions and methods for non-surgical treatment of ptosis
AssigneeVoom, LLC
InventorMark Silverberg
Life of this patent
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Abstract
Provided are pharmaceutical compositions, and methods of use of the compositions, for the non-surgical treatment of ptosis (eyelid droop). In one embodiment the composition includes oxymetazoline 0.1% formulated for topical administration to an eye. In one embodiment the composition includes a synergistic combination of oxymetazoline and phenylephrine, formulated for topical administration to an eye. Oxymetazoline alone causes no pupillary dilation (mydriasis), and a synergistic combination of oxymetazoline and phenylephrine induces no clinically significant mydriasis. In addition to providing desirable cosmetic effects, the compositions and methods of the invention can improve visual fields otherwise compromised by ptosis.
Claims21
-40. (canceled)
A pharmaceutical composition comprising 0.1 weight percent oxymetazoline hydrochloride, wherein the composition has a pH of from 6.5 to 7.8,
- and wherein the composition is suitable for administration to an exterior surface of an eye.
A kit comprising a pharmaceutical composition in a single unit dose container and instructions for administering the composition to an exterior surface of an eye for the treatment of ptosis,
- wherein the pharmaceutical composition comprises 0.1 weight percent oxymetazoline hydrochloride,
- wherein the composition has a pH of from 6.5 to 7.8,
- and wherein the composition is suitable for administration to an exterior surface of an eye.
A method of treating ptosis in a subject in need thereof, the method comprising:
- administering to an exterior surface of an eye of the subject an effective amount of a pharmaceutical composition comprising 0.1 weight percent oxymetazoline hydrochloride, wherein the pH of the composition is from 6.5 to 7.8.
Dependencies are inferred from the claim text.