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US 2026/0272879 A1Published application
Anion-binding aromatic oligoamide macrocycles and methods of making and using same
AssigneeThe Research Foundation for The State University of New York
InventorsBing GONG, Ruikai CAO
Life of this patent
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Abstract
Provided are compounds having the following structure (I) or (II) The compounds may be used to sequester one or more hydrogen-bond acceptors and/or ions. Also provided are methods for making the compounds and methods for using the compounds for treating individuals diagnosed with or suspected of having an extracellular and/or intracellular anion imbalances and/or cystic fibrosis.
Claims22
A compound having the following structure:
- wherein n is 1 or 2, and
- wherein R is independently at each occurrence chosen from substituted or unsubstituted aliphatic groups, substituted or unsubstituted cyclic aliphatic groups, and substituted or unsubstituted aryl groups.
-5. (canceled)
-30. (canceled)
Dependencies are inferred from the claim text.