Formation of co-crystals
AssigneeIndicatrix Crystallography Ltd.
InventorsJessica P. METHERALL, Lina Mardiana, Michael R. PROBERT, Michael J. Hall
Life of this patent
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Abstract
The invention relates to a method of forming a co-crystal, the method comprising forming a droplet comprising a first liquid and a second liquid; wherein the first liquid comprises a chemical molecule, or a salt thereof, and a co-former, or a salt thereof, and the second liquid is an oil. The invention also relates to a method of screening for co-crystals of a chemical molecule, or salt thereof, the method comprising said method of forming a co-crystal.
Claims24
A method of forming a co-crystal comprising a chemical molecule, or a salt thereof, and a co-former, or a salt thereof, the method comprising:
- a1) obtaining a first solution, said first solution comprising the chemical molecule, or the salt thereof, dissolved in an organic medium;
- a2) obtaining a second solution, said second solution comprising the co-former, or the salt thereof, dissolved in an organic medium;
- b) forming a droplet, the droplet comprising a first liquid and a second liquid;
- wherein the first liquid comprises a mixture of the first and second solutions;
- and the second liquid is an oil;
- and
- c) allowing the co-crystal comprising the chemical molecule, or the salt thereof, and the co-former, or the salt thereof, to form in the droplet.
Dependencies are inferred from the claim text.