Ablation treatment devices and methods

An apparatus for delivering a pulsed electric field, the apparatus comprising:

• an elongate shaft;
• and
• a tip region extending distally from the elongate shaft and having an outer diameter, the tip region comprising:
• a first electrode,
• a second electrode distal to the first electrode;
• a spacer between the first electrode and the second electrode;
• and
• a support member concentrically arranged relative to the first and second electrodes,
• wherein the support member (1) physically overlaps with each of the proximal and distal electrodes along a longitudinal axis of the tip region;
• and (2) electrically separated radially and axially from at least one of the first electrode and any components electrically coupled to the first electrode, or the second electrode and any components electrically coupled to the second electrode.

A multi-modal apparatus for delivering a pulsed electric field, the apparatus comprising:

• an elongate shaft;
• and
• a tip region extending distally from the elongate shaft,
• the tip region comprising:
• a first electrode,
• a second electrode distal to the first electrode;
• a spacer between the first electrode and the second electrode;
• and
• at least one aspiration or infusion lumen extending through at least a portion of the tip region,
• wherein the apparatus is configured to deliver a bipolar pulsed electric field to a target tissue and to perform one or more of the following:
• (a) deliver a fluid from the tip region to the target tissue, (b) provide a negative pressure at the tip region to assure a proper contact with the target tissue and/or to facilitate collection of a sample from the target tissue, or (c) both (a) and (b).