Treated sheet materials adapted for use as oral products
AssigneeRAI Strategic Holdings, Inc.
InventorMichael Andrew Zawadzki
Life of this patent
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Abstract
Treated sheet articles for oral use including a treated sheet material are described herein. The sheet material includes a structural component and a treatment composition, which can include one or more substituted 3-(1-methylpyrrolidin-2-yl)pyridines. The material can be used independently as an article for oral use or can be combined with other components. Methods for preparing such materials and articles are also provided herein.
Claims20
A treated sheet article for oral use comprising a treated sheet material, the treated sheet material comprising a structural component and a treatment composition associated therewith,
- wherein the treatment composition comprises one or more active agents selected from:
- (i) a substituted 3-(1-methylpyrrolidin-2-yl)pyridine having a structure according to Formula I:
- wherein R1, R2, R3, and R4 are each independently selected from the group consisting of hydrogen, alkyl, alkoxy, cycloalkyl, alkenyl, alkynyl, aryl, alkylaryl, amino, halogen, and cyano, wherein any of said alkyl, alkoxy, cycloalkyl, alkenyl, alkenyl, alkynyl, aryl, alkylaryl, and amino may optionally be substituted;
- and at least one of R1, R2, R3, and R4 are not hydrogen;
- (ii) a substituted 3-(1-methylpyrrolidin-2-yl)pyridine having a structure according to Formula II:
- wherein R5 and R6 are each independently selected from the group consisting of hydrogen, alkyl, alkoxy, cycloalkyl, alkenyl, alkynyl, aryl, alkylaryl, amino, halogen, and cyano, wherein any of said alkyl, alkoxy, cycloalkyl, alkenyl, alkenyl, alkynyl, aryl, alkylaryl, and amino may optionally be substituted;
- R7 is selected from the group consisting of hydrogen and CH3;
- R8 is selected from the group consisting of hydrogen and C1-C3 alkyl;
- and
- at least one of R7 and R8 is not hydrogen;
- and
- (iii) a 3-(azetidin-2-yl)pyridine or 3-(azetidin-2-ylmethoxy)pyridine having a structure according to Formula III:
- wherein L is a bond or —OCH2—*, where the asterisk indicates an attachment point to the azetidine ring;
- R9, R10, R11, and R12 are each independently selected from the group consisting of hydrogen, alkyl, alkoxy, halogen, and cyano;
- R13 is H or CH3;
- and
- R14 is H or CH3.
Dependencies are inferred from the claim text.