Method for treating a candida auris biofilm covered surface
AssigneeImam Abdulrahman Bin Faisal University
InventorsHanan A. ALDOSSARY, Suriya REHMAN, B. Rabindran JERMY, Sayed ABDULAZEEZ, J. Francis BORGIO, Ebtesam Abdullah AL-SUHAIMI
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Abstract
A method of reducing an amount of a Candida auris biofilm on a surface, including, contacting a composition with the surface, where the composition reduces the amount of the Candida auris biofilm by at least 50% 24 hours after contacting the composition with the surface. The composition includes silicalite, and silver nanoparticles isomorphously substituted in a matrix of the silicalite, where an atomic ratio of Si to Ag is in a range of 25:1 to 1:1. The particles of the composition have a spherical shape and an average size of 400-800 nm.
Claims19
A method of treating a surface having a Candida auris biofilm, comprising:
- contacting a powder composition with the surface, wherein the powder composition attaches to a cell surface of Candida auris cells in the biofilm and at least partially penetrates the Candida auris cells,
- wherein the powder composition reduces an amount of the Candida auris biofilm by at least 50% 24 hours after the contacting,
- wherein the powder composition comprises:
- silicalite;
- and
- silver nanoparticles,
- wherein an atomic ratio of Si to Ag is in a range of 25:1 to 1:1,
- wherein particles of the composition have a spherical shape and an average size of 400-800 nm, and
- wherein the silver nanoparticles have been isomorphously substituted in a matrix of the silicalite.
(canceled)
Dependencies are inferred from the claim text.