System and method for magnetization prepared magnetic resonance imaging

A method for magnetic resonance imaging of tissue to fluid water exchange in a region of interest in a subject, the method comprising:

• acquiring, using a magnetic resonance imaging (MRI) system, magnetic resonance (MR) data for at least two images of the region of interest of the subject using a different timing for application of a T2 preparation for each image;
• generating the at least two images using the corresponding MR data;
• and
• generating an image with signal representing water exchange by comparing the at least two images.

A magnetic resonance imaging (MRI) system comprising:

• a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject;
• a magnetic gradient system including a plurality of magnetic gradient coils configured to apply at least one magnetic gradient field to the polarizing magnetic field;
• a radio frequency (RF) system configured to apply an RF field to the subject and to receive magnetic resonance signals from the subject using a coil array;
• and
• a computer system programmed to:
• acquire magnetic resonance (MR) data for at least two images of the region of interest of the subject using a different T2 preparation for each image;
• generate the at least two images using the corresponding MR data;
• and
• generate an image with signal representing water exchange by comparing the at least two images.

A magnetic resonance imaging (MRI) system comprising:

• a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject;
• a magnetic gradient system including a plurality of magnetic gradient coils configured to apply at least one magnetic gradient field to the polarizing magnetic field;
• a radio frequency (RF) system configured to apply an RF field to the subject and to receive magnetic resonance signals from the subject using a coil array;
• and
• a computer system programmed to:
• acquire magnetic resonance (MR) date for at least two images of the region of interest of the subject using a different timing for application of a T2 preparation for each image;
• generate the at least two images using the corresponding MR data;
• and
• generate an image with signal representing water exchange by comparing the at least two images.

A method for velocity selective arterial spin labeling magnetic resonance imaging of tissue perfusion in a region of interest in a subject, the method comprising:

• acquiring, using a magnetic resonance imaging (MRI) system, magnetic resonance (MR) data for at least two images of the region of interest of the subject using a different timing for application of a velocity selective preparation for each image;
• generating the at least two images using the corresponding MR data;
• and
• generating an image with signal representing perfusion by comparing the at least two images.