Protein biomarker indicators of neurological injury and/or disease and methods of use thereof
AssigneeBrainbox Solutions, Inc.
InventorTimothy E. VAN METER
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AssigneeBrainbox Solutions, Inc.
InventorTimothy E. VAN METER
Estimating the term…
Methods, compositions and kits useful in the detection, assessment, diagnosis, prognosis and/or treatment of neurological injury or disease or brain injury, such as traumatic brain injury (TBI), are provided in which certain newly discovered protein biomarkers are detected in a biological sample of a subject undergoing testing or evaluation. The methods allow for detection of changes in levels, amounts, or concentrations of the protein biomarkers in a subject compared with those of controls. Detection of the protein biomarkers, and/or levels thereof, provides an indication of biological and biochemical events, e.g., at a cellular level, that are occurring in the subject who is undergoing testing or analysis for the neurological injury or brain injury.
A method of detecting protein biomarkers, or peptide biomarkers derived therefrom, indicative of neurological or brain injury in a subject, the method comprising detecting whether one or more protein biomarkers, or peptide biomarkers derived therefrom, are present in a biological sample obtained from the subject by using a protein detection assay, wherein the one or more protein biomarkers are selected from protein Nos. 1-81 from Table 1.
Dependencies are inferred from the claim text.