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US 2026/0265684 A1Published application
Eimeria vaccine
AssigneeEimeria Pty. Limited
InventorsVladimir Vrba, Sarika Kosaraju
Life of this patent
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Abstract
The present disclosure relates to methods and compositions for the production of oocysts from protozoa, such as Eimeria. The present disclosure also relates compositions comprising the oocysts and use of these composition for the treatment and/or prevention of infections.
Claims27
A method for preparing a formulation comprising viable Eimeria oocysts, the method comprising:
- incubating viable oocysts with a sporulating composition comprising a first concentration of peroxycarboxylic acid to produce viable, sporulated Eimeria oocysts;
- and
- incubating the viable, sporulated Eimeria oocysts with a sterilising composition comprising a second concentration of the peroxycarboxylic acid to produce the formulation,
- wherein the second concentration of peroxycarboxylic acid is greater than the first concentration.
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A method for sporulating viable Eimeria oocysts comprising:
- incubating the oocysts with a sporulating composition comprising a first concentration of peroxycarboxylic acid to produce viable, sporulated Eimeria oocysts,
- wherein the first concentration of peroxycarboxylic acid comprises less than 20,000 ppm peroxycarboxylic acid.
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A composition comprising:
- i) Eimeria oocysts and peroxycarboxylic acid at a concentration of less than 20,000 ppm;
- and/or
- ii) a population of sporulated Eimeria oocysts, wherein the composition is sterile and, wherein the sporulated oocysts have been treated with a first concentration of peroxycarboxylic acid and a second concentration of peroxycarboxylic acid in a single vessel, wherein the first concentration of peroxycarboxylic acid is less than 1000 ppm and the second concentration of peroxycarboxylic acid increased relative to the first concentration.
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Dependencies are inferred from the claim text.