Peptide targeting gip and glp-2 receptors for treating bone disorders
AssigneesUniversite D'Angers, Centre Hospitalier Universitaire D'Angers
InventorsGuillaume MABILLEAU, Aleksandra MIECZKOWSKA
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Abstract
The present invention concerns an isolated peptide comprising the consensus amino acid sequence SEQ ID NO: 1: (SEQ ID NO: 1) HGEGSFX7SDX10 SX12X13LDKLAARDFVNWLLQTK wherein X7 is any amino acid residue, X10 is any amino acid residue, X12 is any amino acid residue and X13 is any amino acid residue, and the use thereof in the treatment of bone disorders.
Claims16
An isolated peptide comprising the consensus amino acid sequence SEQ ID NO:
- 1:
- (SEQ ID NO:
- 2)
- HGEGSFX7SDX10 SX12X13LDKLAARDFVNWLLQTKITD,
- wherein X7 is any amino acid residue, X10 is any amino acid residue, X12 is any amino acid residue and X13 is any amino acid residue.
An isolated peptide comprising an amino acid sequence selected from the group consisting of the amino acid sequences:
- GL-0001 of sequence
- (SEQ ID NO:
- 3)
- HGEGSFGSDMSIALDKLAARDFVNWLLQTKITD,
- GL-0007 of sequence
- (SEQ ID NO:
- 4)
- HGEGSFGSDFSIALDKLAARDFVNWLLQTK-NH2,
- GL-0001-Tag of sequence
- (SEQ ID NO:
- 5)
- HGEGSFGSDMSIALDKLAARDFVNWLLQTKITDGAADDDDDD,
- GL-0002 of sequence
- (SEQ ID NO:
- 6)
- HGEGSFVSDMSIVLDKLAARDFVNWLLQTK-NH2,
- GL-0003 of sequence
- (SEQ ID NO;
- 7)
- HGEGSFVSEMSIVLDKLAARDFVNWLLQTK-NH2,
- GL-0004 of sequence
- (SEQ ID NO:
- 8)
- HGEGSFVSDMSVVLDKLAARDFVNWLLQTK-NH2,
- GL-0005 of sequence
- (SEQ ID NO:
- 9)
- HGEGSFVSDLSVVLDKLAARDFVNWLLQTK-NH2,
- GL-0006 of sequence
- (SEQ ID NO:
- 10)
- HGEGSFVSDFSVVLDKLAARDFVNWLLQTK-NH2,
- GL-0008 of sequence
- (SEQ ID NO:
- 11)
- HGEGSFTSDFSIALDKLAARDFVNWLLQTK-NH2,
- and
- GL-0009 of sequence
- (SEQ ID NO:
- 12)
- HGEGSFVSDFSIALDKLAARDFVNWLLQTK-NH2.
Dependencies are inferred from the claim text.