Novel benzimidazolone derivative compound as autotaxin inhibitor

A compound having a chemical structure of Formula 1 below or a pharmaceutically acceptable salt thereof:

• wherein, in Formula 1 above,
• Q1 and Q2 are each independently any one selected from the group consisting of:
• carbon;
• and nitrogen,
• X1 and X2 are each independently any one selected from the group consisting of:
• hydrogen;
• halogen;
• substituted or unsubstituted alkyl;
• substituted or unsubstituted cycloalkyl;
• and substituted or unsubstituted alkoxy,
• A is aryl;
• or heteroaryl,
• X3, X4, and X5 are each independently any one selected from the group consisting of:
• hydrogen;
• halogen;
• hydroxy;
• oxo;
• carboxy;
• substituted or unsubstituted alkoxy;
• substituted or unsubstituted thio;
• substituted or unsubstituted amino;
• substituted or unsubstituted carbamoyl;
• substituted or unsubstituted sulfonyl;
• substituted or unsubstituted alkyl;
• substituted or unsubstituted cycloalkyl;
• substituted or unsubstituted tricycloalkyl;
• substituted or unsubstituted heterocycloalkyl;
• substituted or unsubstituted oxoheterocycloalkyl;
• substituted or unsubstituted heterobicycloalkyl;
• substituted or unsubstituted cycloalkenyl;
• substituted or unsubstituted heterocycloalkenyl;
• substituted or unsubstituted oxaazabicycloalkyl;
• substituted or unsubstituted aryl;
• substituted or unsubstituted heteroaryl;
• substituted or unsubstituted heterocycloalkylcarbonyl;
• and substituted or unsubstituted heterobicycloalkylcarbonyl,
• the substituted functional groups in X3, X4, and X5 above are each independently substituted with at least one selected from the group consisting of:
• halogen;
• hydroxy;
• alkoxy;
• alkoxycarbonyl;
• sulfonyl;
• alkylsulfonyl;
• haloalkylsulfonyl;
• oxo;
• alkyl;
• haloalkyl;
• hydroxyalkyl;
• cycloalkyl;
• halocycloalkyl;
• heterocycloalkyl;
• alkyloxoheterocycloalkyl;
• aryl;
• heteroaryl;
• haloalkylheteroaryl;
• acetyl;
• alkylcarbonyl;
• haloalkylcarbonyl;
• cycloalkylcarbonyl;
• halocycloalkylcarbonyl;
• heterocycloalkylcarbonyl;
• haloheterocycloalkylcarbonyl;
• hydroxyheterocycloalkylcarbonyl;
• alkylheterocycloalkylcarbonyl;
• alkylamino;
• cycloalkylamino;
• cycloalkylalkylamino;
• and alkylaminocarbonyl,
• n is an integer of 0 to 3,
• R1 and R2 are each independently any one selected from the group consisting of:
• hydrogen;
• a substituted or unsubstituted alkyl group;
• and a substituted or unsubstituted cycloalkyl group, or R1 and R2 above are linked to each other to form a substituted or unsubstituted hydrocarbon ring,
• B is aryl;
• or heteroaryl,
• X6 and X7 are each independently any one selected from the group consisting of:
• hydrogen;
• halogen;
• hydroxy;
• oxo;
• substituted or unsubstituted alkoxy;
• substituted or unsubstituted amino;
• substituted or unsubstituted alkyl;
• and substituted or unsubstituted cycloalkyl, and
• the substituted functional groups in X1, X2, X6, X7, R1, and R2 above are substituted with at least one selected from the group consisting of halogen, alkyl, hydroxyalkyl, alkoxyalkyl, haloalkyl, cycloalkyl, heterocycloalkyl, —OR3, —(CO)—R3, —(CO)—OR3, alkylamino, and oxo, wherein R3 is hydrogen or alkyl.