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US 2026/0265173 A1Published application
Selective Serotonin Receptor Modulators and Methods of Making and Using the Same
AssigneePark City Bio, LLC
InventorJeremy Forest
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Abstract
This disclosure relates to serotonin receptor modulators, including conformationally constrained serotonin receptor agonists, and methods of making and using the same are disclosed herein.
Claims20
A compound selected from Formula V:
- wherein
- X and Y are each hydrogen;
- W1 is O;
- W3 is C(R10)(R11);
- n is 1;
- W4 is C(R12)(R13) for each occurrence;
- m is an integer selected from 1 and 2;
- R10, R11, R12 and R13 are, for each occurrence, independently selected from hydrogen and deuterium;
- R15 is selected from hydrogen, deuterium and fluoro;
- R4, R6, and R7 are each hydrogen;
- R5 is fluoro;
- R3 and R3′ are independently selected from hydrogen and deuterium, provided that at least one of R3, R3′, R10 or R11 is deuterium,
- and salts, solvates, hydrates, prodrugs, and enantiomers thereof.
10 more elements
Dependencies are inferred from the claim text.