Combination of bifidobacterium and fucosylated hmo for use in increasing nmn or nad+

Abstract

The present disclosure relates to a method of increasing nicotinamide mononucleotide (NMN) and/or nicotinamide adenine dinucleotide (NAD+) in the gut of a subject by administering a combination comprising at least one Bifidobacterium sp. capable of growing on a sialylated HMO and having a functional de novo nicotinamide adenine dinucleotide (nad) operon (nadC, nadD and nadE) and at least one fucosylated oligosaccharide to said subject.

Dependencies are inferred from the claim text.