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US 2026/0263530 A1Published application
Compositions and methods relating to pooled fetal support tissue
AssigneeBiotissue Holdings Inc.
InventorsScheffer TSENG, Ek Kia TAN, Lorraine CHUA
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Abstract
Described herein is a composition, methods comprising, pooled fetal support tissue, wherein the pooled fetal support tissue comprises a therapeutically effective amount of native HC-HA/PTX3 complex.
Claims18
1-85. (canceled)
A composition comprising a pooled fetal support tissue, wherein the pooled fetal support tissue comprises fetal support tissue from a plurality of donors, wherein the pooled fetal support tissue comprises a native HC-HA/PTX3 (nHC-HA/PTX3) complex, wherein the composition comprises:
- (a) a total protein content, wherein the total protein content determined by a bicinchoninic acid protein (BCA) assay is at least about 200 μg/mL;
- (b) a hyaluronic acid (HA) content, wherein the HA content determined by an HA assay is at least about 80 μg/mL;
- and
- (c) TRAP activity, wherein the composition inhibits TRAP activity by at least about 25% when compared with 50 μg/ml of RANKL.
1 more element
Dependencies are inferred from the claim text.