Systems and methods for delivering drugs to retinal tissue
AssigneeClearside Biomedical, Inc.
InventorsRafael Victor ANDINO, Thomas Edward GODFREY, Shelley Eckert HANCOCK, Samirkumar PATEL, Keleigh Jo MAHN, Jesse YOO, Vladimir ZARNITSYN
Life of this patent
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Abstract
Devices, methods, and kits for ocular drug delivery are described herein. In some embodiments, a method includes inserting a distal end portion of a puncture member into an eye to define a delivery passageway within the eye. The delivery passageway extends through ha sclera of the eye and a choroid of the eye. The delivery passageway is less than about 1.5 mm. The method further includes conveying a substance into a subretinal space within the eye via the distal end portion of the puncture member.
Claims21
A method, comprising:
- inserting a distal end portion of a puncture member into an eye to define a delivery passageway within the eye extending through a sclera of the eye and a choroid of the eye, a length of the delivery passageway being less than about 1.5 mm;
- and
- conveying a substance into a subretinal space within the eye via the distal end portion of the puncture member.
A method, comprising:
- inserting a distal end portion of a puncture member into an eye;
- moving the distal end portion of the puncture member in a first direction until a tip of the puncture member penetrates a sclera of the eye, a choroid of the eye, and a retina of the eye;
- moving the distal end portion of the puncture member in a second direction until the tip of the puncture member moves from within the retina into a subretinal space of the eye, the second direction opposite the first direction;
- and
- conveying a substance into at least one of the subretinal space within the eye, a supraciliary space within the eye, or a ciliary space within the eye, via the distal end portion of the puncture member.
A method, comprising:
- inserting a distal end portion of a delivery portion of a delivery assembly of a medical injector into a target tissue to define a delivery passageway within the target tissue;
- conveying, via the delivery assembly, a first substance into a first region of the target tissue, the first substance formulated to produce a seal within the first region;
- moving, after the conveying, the distal end portion through the first region of the target tissue;
- and
- conveying, via the delivery assembly, a second substance into a second region of the target tissue, the second substance formulated to include an active ingredient.
Dependencies are inferred from the claim text.