Method and system for screening spaceflight-associated neuro-ocular syndrome and applications of same
AssigneeAugusta University Research Institute, Inc.
InventorMatthew Lyon
Life of this patent
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Abstract
One aspect of the invention relates to a method for screening SANS for a living subject comprising obtaining 3D images or 3D quantitative measurements of at least one optic nerve sheath of the living subject at rest and with a provocative maneuver, respectively, prior to a spaceflight, wherein the 3D images or the 3D quantitative measurements obtained at rest is used as a baseline; evaluating the 3D images or the 3D quantitative measurements obtained at rest and with the provocative maneuver; and determining if the living subject is at risk of developing the SANS based on the evaluation of the 3D images or the 3D quantitative measurements.
Claims52
A method for screening spaceflight-associated neuro-ocular syndrome (SANS) for a living subject, comprising:
- obtaining three-dimensional (3D) images or 3D quantitative measurements of at least one optic nerve sheath (ONS) of the living subject at rest and with a provocative maneuver, respectively, prior to a spaceflight, wherein the 3D images or the 3D quantitative measurements obtained at rest is used as a baseline;
- evaluating the 3D images or the 3D quantitative measurements obtained at rest and with the provocative maneuver;
- and
- determining if the living subject is at risk of developing the SANS based on the evaluation of the 3D images or the 3D quantitative measurements.
A method for screening spaceflight-associated neuro-ocular syndrome (SANS) for a living subject, comprising:
- obtaining three-dimensional (3D) images or 3D quantitative measurements of at least one optic nerve sheath (ONS) of the living subject at rest in a normal gravity environment prior to a spaceflight and during the spaceflight and/or on a space station in a low-or no-gravity environment, respectively, wherein the 3D images or the 3D quantitative measurements obtained at rest in the normal gravity environment is used as a baseline;
- evaluating the 3D image or the 3D quantitative measurement obtained during the spaceflight and/or on the space station in the low-or no-gravity environment by comparing them with the baseline;
- and
- determining a degree of predisposition to developing the SANS, an efficacy of SANS treatments or countermeasures, and/or an ongoing injury during the spaceflight and/or on the space station in the low-or no-gravity environment based on the evaluation of the 3D images or the 3D quantitative measurements.
A system for screening spaceflight-associated neuro-ocular syndrome (SANS) for a living subject, comprising:
- a means for obtaining three-dimensional (3D) images or 3D quantitative measurements of at least one optic nerve sheath (ONS) of the living subject at rest and with a provocative maneuver, respectively, prior to a spaceflight, wherein the 3D images or the 3D quantitative measurements obtained at rest is used as a baseline;
- and
- a processor for evaluating the 3D images or the 3D quantitative measurements obtained at rest and with the provocative maneuver;
- and determining if the living subject is at risk of developing the SANS based on the evaluation of the 3D images or the 3D quantitative measurements.
Dependencies are inferred from the claim text.