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US 2026/0262968 A1Published application
Grooved microneedles for passive and active sampling of interstitial fluids
AssigneeTrustees of Tufts College
InventorSameer Sonkusale
Life of this patent
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Abstract
Disclosed are systems and methods for sampling a fluid from a region of interest of a subject. The sampling system includes a patch including at least one grooved microneedle coupled thereto, a collection reservoir coupled to the patch, and a sensor coupled to the collection reservoir. The at least one grooved microneedle defines a fluid channel therein, and the collection reservoir is in fluid communication with the fluid channel of the at least one grooved microneedle.
Claims20
A sampling system comprising:
- a patch including at least one grooved microneedle coupled thereto;
- a collection reservoir coupled to the patch;
- and
- a sensor coupled to the collection reservoir,
- wherein the at least one grooved microneedle defines a fluid channel therein, and
- wherein the collection reservoir is in fluid communication with the fluid channel of the at least one grooved microneedle.
3 more elements
A system for sampling a fluid of a subject, comprising:
- a patch including at least one microneedle coupled to a first side thereof;
- and
- a sensor to detect a presence of at least one biomarker in the fluid that is drawn through the at least one microneedle,
- wherein the at least one microneedle includes a body with a central channel therein, the central channel being in fluid communication with a groove disposed on an exterior of the body.
1 more element
A method of sampling interstitial fluid, the method comprising:
- placing, on a subject's skin, a microneedle patch including at least one microneedle coupled a first side of the microneedle patch and a collection reservoir coupled to a second side of the microneedle patch,
- providing a suction force to the microneedle patch to direct a fluid through the at least one microneedle and into the collection reservoir;
- and
- detecting, with a sensor coupled to the collection reservoir, at least one of a presence or a concentration of a biomarker in the fluid.
1 more element
Dependencies are inferred from the claim text.