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US 2026/0259222 A1Published application
Method of diagnosing wounds
AssigneeTRAUMA CARE CONSULT Traumatologische Forschung Gemeinnützige Gesellschaft mbH
InventorsMikolaj OGRODNIK, Nadja Anneliese Ruth RING, Helene DWORAK, Barbara SCHÄDL, Heinz REDL
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Abstract
The present invention discloses a method comprising measuring an individual level or amount of presence, expression or activation of phosphorylated ribosomal protein S6 (p-rpS6) in a sample from a wound.
Claims15
A method comprising the following steps:
- measuring the presence or absence of phosphorylated ribosomal protein S6 (p-rpS6) in a sample from a wound of a patient;
- and
- identifying the absence of p-rpS6 in the sample as being indicative for a lack of vascularisation and/or lack of oxygenation of the wound and/or presence of necrotic tissue within the wound.
A method for identifying necrotic tissue within a wound comprising the following steps:
- measuring the presence or absence of phosphorylated ribosomal protein S6 (p-rpS6) in a sample from a wound;
- and
- identifying the area from which the sample of the wound was derived as being necrotic tissue;
- and, if applicable,
- removing the necrotic tissue from the wound.
2 more elements
A method comprising the following steps:
- measuring an individual level or amount of presence, expression or activation of phosphorylated ribosomal protein S6 (p-rpS6) in a sample from a wound of a patient;
- comparing the measured individual amount or level of p-rpS6 of the sample with a standard level or amount of p-rpS6 to assess tissue response to wounding;
- and
- in case the comparison results in an assessment of impaired tissue response to wounding administering an effective amount of a therapeutic agent for improving wound healing in the patient.
1 more element
A method comprising the following steps:
- measuring an individual level or amount of presence, expression or activation of phosphorylated ribosomal protein S6 (p-rpS6) in a sample from a wound;
- and
- diagnosing an impaired wound healing risk if the measured individual amount or level of p-rpS6 of the sample is increased in comparison with the amount or level of a wound sample of a patient which is not affected by an impaired wound healing risk.
Dependencies are inferred from the claim text.