Method of detecting glucose
AssigneeImam Abdulrahman Bin Faisal University
InventorsTahani ALFAREED, Jwaher M. ALGHAMDI, Emre CEVIK
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Abstract
A composite is provided which comprises planar molybdenum oxide microstructures and cobalt oxyhydroxide microstructures disposed on the planar molybdenum oxide microstructures. A method of forming the composite is also provided. The composite is used in the fabrication of an electrochemical sensor, which comprises the composite, an electrode, and a polymeric coating. The electrochemical sensor is used in a method of detecting the presence of glucose in an analyte. The method involves applying a voltage to the electrochemical sensor relative to a counter electrode and measuring a current response. The method in insensitive to common oxidative interfering analytes such as urea, lactate, and NaCl.
Claims14
1-12. (canceled)
A method of detecting glucose, comprising:
- immersing a working electrode comprising an electrochemical sensor, a reference electrode, and a counter electrode in an aqueous sample having a pH of from 8 to 11 and comprising a hydroxide base, wherein the electrochemical sensor comprises a sensor electrode made from a sensor composite and a polymeric coating disposed on the sensor composite,
- wherein the sensor composite comprises:
- planar molybdenum oxide microstructures having a mean thickness of 0.5 to 5 μm and a mean width of 1 to 10 μm;
- and
- cobalt oxyhydroxide microstructures having a mean size of 1 to 8 μm disposed on a surface of the planar molybdenum oxide microstructures,
- wherein the molybdenum oxide is crystalline by PXRD and the cobalt oxyhydroxide is crystalline by PXRD;
- applying a voltage to the working electrode and counter electrode;
- measuring a current response to determine at least one selected from a cathodic peak voltage, an anodic peak voltage, and a steady-state current;
- and
- determining the presence of glucose in the analyte based on at least one selected from the group consisting of the cathodic peak voltage, the anodic peak voltage, and the steady-state current.
Dependencies are inferred from the claim text.