Immune inducer
AssigneeToray Industries, Inc.
InventorsAkira KURIHARA, Fumiyoshi OKANO
Life of this patent
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Abstract
An object of the present invention is to discover a novel peptide useful as an active ingredient in an agent for treating or preventing cancer, and to provide the use of the polypeptide as an immune inducer. The immune inducer containing as an active ingredient: (a) a polypeptide consisting of any one of the amino acid sequences represented by SEQ ID NOs: 35 to 67; or (b) a polypeptide comprising one to several amino acid deletions, substitutions and/or additions in the amino acid sequence of the polypeptide (a); is useful as an agent for treating or preventing cancer, etc.
Claims5
A method of treating or preventing cancer, comprising administering an immune inducer for treating or preventing said cancer;
- wherein the immune inducer comprises, as an active ingredient, the following (i) or (ii):
- (i) at least one polypeptide having an immune-inducing activity and selected from the group of polypeptides (a) or (b) below:
- (a) polypeptides consisting of 7 or more consecutive amino acids within the region of positions 24 to 97, positions 113 to 132, positions 134 to 197, positions 204 to 225, positions 265 to 332, positions 378 to 463, positions 472 to 498, positions 533 to 567, positions 613 to 643, positions 671 to 735, positions 737 to 780, positions 792 to 830, positions 832 to 899, positions 920 to 943, positions 946 to 993, positions 1029 to 1069 and positions 1074 to 1215 in the amino acid sequence represented by SEQ ID NO:
- 2;
- (b) polypeptides comprising one to several amino acid deletions, substitutions and/or additions in the amino acid sequence of any one of the polypeptides (a);
- and
- (ii) a recombinant vector comprising at least one polynucleotide encoding any one of the polypeptides (i), and capable of expressing the polypeptide in vivo.
Dependencies are inferred from the claim text.