Co-crystal forms of selinexor
AssigneeKaryopharm Therapeutics Inc.
InventorClifton R. Hamilton
Life of this patent
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Abstract
The present invention is directed to selinexor co-crystal forms; more particularly to two co-crystal forms with succinic acid as the coformer and a co-crystal form with vanillin as the coformer. The present disclosure is also related to processes for the preparation of selinexor co-crystal forms. Further, the present invention also relates to pharmaceutical compositions comprising a selinexor co-crystal form and method for treating disease using a selinexor co-crystal form.
Claims21
1-16. (canceled)
A method of treating cancer comprising administering a therapeutically effective amount of a selinexor co-crystal to a subject in need thereof, wherein the selinexor co-crystal comprises selinexor and succinic acid as a coformer.
A method of treating cancer comprising administering a therapeutically effective amount of a selinexor co-crystal to a subject in need thereof, wherein the selinexor co-crystal comprises selinexor and vanillin as a coformer.
Dependencies are inferred from the claim text.