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US 2026/0257988 A1Published application
Benzaldehyde oximes and method for producing same
AssigneeBayer Aktiengesellschaft
InventorAndreas REMBIAK
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Abstract
The present invention relates to a method for preparing benzaldehyde oximes of the general formula (I) and to the use thereof as important precursors for the synthesis of agrochemical and pharmaceutical active substances.
Claims14
Method for preparing compounds of the formula (I)
- in which
- X2 is H, C1-C4 alkyl, C1-C4 fluoroalkyl, C1-C4 fluoroxyalkyl, C1-C4 alkoxy, fluorine, CN,
- X3 is H, C1-C4 alkyl, C1-C4 fluoroalkyl, C1-C4 fluoroxyalkyl, C1-C4 alkoxy, fluorine, chlorine, CN,
- X4 is H, C1-C4 alkyl, C1-C4 fluoroalkyl, C1-C4 fluoroxyalkyl, C1-C4 alkoxy, fluorine, CN,
- X5 is H, C1-C4 alkyl, C1-C4 fluoroalkyl, C1-C4 fluoroxyalkyl, C1-C4 alkoxy, fluorine, chlorine, CN,
- X6 is H, C1-C4 alkyl, C1-C4 fluoroalkyl, C1-C4 fluoroxyalkyl, C1-C4 alkoxy, fluorine, CN,
- and wherein the compounds of the general formula (II)
- in which the radicals are as defined above,
- are in a first reaction step reacted in the presence of isopropylmagnesium chloride and DMF to form corresponding adducts (III), which in a second reaction step with addition of acid and hydroxylamine react further to aldehydes of the general formula (IV)
- in which the radicals are as defined above,
- with the subsequent formation of the compounds of the general formula (I).
8 more elements
Dependencies are inferred from the claim text.