Systems and devices for filtering biological products and methods of using the same
OwnerJohn Michael D'Orsi, III, Chad David Hauze +1inventors
InventorsJohn Michael D'Orsi, III, Chad David Hauze, Peer Christian Wespestad
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Abstract
Systems and devices for filtering biological products and methods of using the same are provided. A filtration system can include a filtration skid configured to be adapted for engagement with components of a single-use assembly for facilitating one or more unit operations of a continuous filtering process for the one or more biological products. The filtration skid can include a pump cart and a filtration cart. The filtration cart can include a first filter support assembly configured to support a first filtering flow channel and a second filter support assembly configured to support a second filtering flow channel.
Claims22
A filtration system for filtering one or more biological products, comprising:
- a filtration skid configured for engagement with components of a single-use assembly for facilitating one or more unit operations of a continuous filtering process for the one or more biological products, the filtration skid comprising a pump cart and a filtration cart, the filtration cart comprising:
- a first filter support assembly configured to support a first filtering flow channel;
- and
- a second filter support assembly configured to support a second filtering flow channel.
A method for a continuous filtering process using a filtration skid comprising:
- initializing a single-use assembly and a filtration skid, wherein the single-use assembly comprises a plurality of filters, the filtration skid comprises a first filter support assembly and a second filter support assembly;
- wetting a first filter of the plurality of filters with buffer, wherein the first filter is coupled to the first filter support assembly;
- conditioning the first filter with a first biological product;
- dispensing the first biological product to a first filler after passing through the first filter while wetting a second filter of the plurality of the filters with the buffer, the first filler receiving a first filtered biological product from the first filter, the second filter coupled to the second filter support assembly;
- conditioning the second filter with a second biological product;
- and
- dispensing the second biological product to a second filler after passing through the second filter.
Dependencies are inferred from the claim text.