Manufacture of adipose-derived human adult mesenchymal stromal cells
AssigneesTheracell Laboratories, Orgenesis Inc.
InventorsFOTIOS SAKELLARIDIS, POLYCHRONIS FATOUROS, MARIA KONTOU
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Abstract
Disclosed herein is an autologous composition comprising mesenchymal stem stromal cells, wherein the mesenchymal stem stromal cells are derived from adipose tissue collected by punch biopsy from a subject, and the use for the treatment of a disease, including a disease with arthritic lesion progression.
Claims26
An autologous composition comprising mesenchymal stromal cells, wherein said mesenchymal stromal cells are derived from adipose tissue collected by punch biopsy from a subject.
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A method for the preparation of a composition comprising autologous mesenchymal stromal cells, comprising the step of collecting adipose tissue by punch biopsy.
A method for delaying osteoarthritic lesion progression, inducing repair and regeneration of inflamed/destructed tissue, or combination thereof, in a subject, comprising administering an autologous composition comprising mesenchymal stromal cells, wherein said mesenchymal stromal cells are derived from adipose tissue collected by punch biopsy from a subject, wherein said subject in need of delaying osteoarthritic lesion progression, inducing repair and regeneration of inflamed/destructed tissue or any combination thereof.
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Dependencies are inferred from the claim text.