Dermal fillers
AssigneeSpiderwort Inc.
InventorsKama Szereszewski, Ryan Hickey, Andrew E. Pelling, Maxime LEBLANC LATOUR, Mark STROOBACH, Pavel MILMAN, Christopher ODDING, Paula Cristina de Sousa Faria Tischer
Life of this patent
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Abstract
Provided herein are dermal fillers including decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed; as well as methods and uses thereof for cosmetic and/or reconstructive applications. Also provided are methods for preparing such dermal fillers, and dermal filler kits.
Claims22
A method for improving cosmetic appearance, increasing tissue volume, smoothing wrinkles, or any combinations thereof, in a subject in need thereof, said method comprising:
- administering or injecting a dermal filler comprising decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, wherein the decellularized plant or fungal tissue is disassembled into particles having a size, diameter, or minimum feret diameter of at least about 20 μm to a region in need thereof;
- thereby improving cosmetic appearance, increasing tissue volume, smoothing wrinkles, or any combinations thereof, of the subject.
A method for preparing a non-resorbable dermal filler, comprising:
- providing a plant or fungal tissue;
- decellularizing and size-reducing the plant or fungal tissue to provide particles from which cellular materials and nucleic acids of the tissue are removed;
- wherein the particles have a size, diameter, or minimum feret diameter of at least about 20 μm and
- optionally, sterilizing the particles;
- thereby providing the non-resorbable dermal filler.
Dependencies are inferred from the claim text.