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US 2026/0256733 A1Published application
Compositions and methods for modulating stress and uses thereof
AssigneeBrightseed, Inc.
InventorsNicholas WOODWARD, Chuan WANG, Ilan Edmond CHEMMAMA, Pranatchareeya CHANKHAMJON, Meng XU, Lee Heil CHAE
Life of this patent
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Abstract
Disclosed herein are compositions and methods for treating, preventing, reducing, modulating, or ameliorating stress, symptoms of stress, or deleterious effects of chronic stress, by providing the composition and a carrier. The methods may include, for example, administering a therapeutically effective compound of a plant extract. The compositions and methods may be capable of modulating mGlu2 and/or mGlu3 receptors.
Claims22
A use of one or more compounds of Formula (I):
- or a salt thereof in the manufacture of a composition for modulating a metabotropic glutamate receptor;
- wherein R1, R2, R3, and R4 are each independently selected from hydrogen, deuterium, hydroxyl, halogen, keto, optionally substituted ester, optionally substituted aryl, optionally substituted alkoxy, optionally substituted C1-C6-alkyl, optionally substituted —O—C1-C6-alkyl, or optionally substituted C3-C6 cycloalkyl.
(canceled)
A use of one or more compounds selected from:
- or a combination thereof in the manufacture of a composition for modulating a metabotropic glutamate receptor.
22-50. (canceled)
Dependencies are inferred from the claim text.