Artificial cartilage implant and manufacturing method therefor

An artificial cartilage implant, comprising:

• a bone implant section including a polymer gel and hydroxyapatite particles dispersed at least in a vicinity of a surface of the polymer gel;
• and
• an artificial cartilage section including a polymer gel, wherein
• when a cross section of the polymer gel of the artificial cartilage section is observed, no hydroxyapatite particle is distributed in a region from a surface of the polymer gel of the artificial cartilage section to a depth of 1000 μm, or in a case where hydroxyapatite particles are distributed in the region, a content of the hydroxyapatite particles at the depth of 1000 μm from the surface is less than 0.1% by weight,
• the polymer gel of the bone implant section and the polymer gel of the artificial cartilage section each include a first mesh structure and a second mesh structure that is entangled with the first mesh structure,
• the first network structure and the second network structure are each crosslinked by a crosslinking agent, and 50 mol % or more of the crosslinking agent includes no degradable bond selected from the group consisting of an ester bond, an amide bond, and a thioester structure, and
• when a cross section of the polymer gel of the bone implant section is observed:
• the hydroxyapatite particles are distributed in a region from the surface of the polymer gel of the bone implant section to a depth of 1000 μm in a central axis direction of the polymer gel of the bone implant section,
• a content of the hydroxyapatite particles at the depth of 1000 μm from the surface in the central axis direction is 0.1% by weight to 80% by weight, and
• an amount of the hydroxyapatite particles distributed in a region from the surface to a depth of 500 μm in the central axis direction is greater than an amount of the hydroxyapatite particles distributed in a region from the depth of 500 μm to the depth of 1000 μm in the central axis direction.