Systems and methods for heart valve therapy
AssigneeCaisson Interventional, LLC
InventorsKavitha Ganesan, Ramji Iyer, Lucas T. Schneider, Todd J. Mortier, Cyril J. Schweich, JR.
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Abstract
Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Deployment systems and methods for using the deployment systems described herein facilitate implanting a two-part prosthetic heart valve that is arranged in a nested configuration during the transcatheter delivery and deployment processes.
Claims17
A transcatheter mitral valve replacement system for a heart, comprising:
- a delivery sheath having a distal end portion insertable into a left atrium;
- a delivery catheter slidably disposed within the delivery sheath;
- and
- a two-part prosthetic mitral valve coupled to the delivery catheter by one or more control wires, the two-part prosthetic mitral valve configured to be disposed within the delivery sheath in a radially compressed condition and to radially self-expand when the two-part prosthetic mitral valve is outside of the delivery sheath and is unconstrained by the one or more control wires, the two-part prosthetic mitral valve comprising:
- a valve assembly including an expandable valve frame and a tri-leaflet occluder;
- and
- an anchor assembly separately expandable from the valve assembly and defining an interior space within which the valve assembly is nested while the two-part prosthetic mitral valve is within the delivery sheath for simultaneous deployment from the delivery sheath.
A method for deploying a transcatheter prosthetic mitral valve system within a native mitral valve of a patient, the method comprising:
- navigating a delivery sheath within the vasculature of the patient such that a distal end portion of the delivery sheath is positioned within a left atrium of the patient, the delivery sheath containing a two-part prosthetic mitral valve in a radially compressed condition and comprising:
- a valve assembly including an expandable valve frame and a tri-leaflet occluder;
- and
- an anchor assembly including an expandable anchor frame separate from the expandable valve frame of the valve assembly and defining an interior space within which the valve assembly is disposed while the two-part prosthetic mitral valve is within the delivery sheath;
- expressing, in the left atrium, the two-part prosthetic mitral valve, wherein a delivery catheter is releasably engaged with the two-part prosthetic mitral valve using one or more control wires, the valve assembly remaining disposed within the interior space defined by the anchor assembly during and after the expressing;
- engaging the anchor assembly with the native mitral valve, wherein the anchor assembly is in a radially expanded condition while engaged with the native mitral valve;
- and
- after the engaging the anchor assembly in the radially expanded condition, expanding the valve assembly within the interior space to couple the valve assembly to the anchor assembly.
A two-part prosthetic heart valve having two separately expandable components arranged in a nested configuration for transcatheter delivery to a heart, comprising:
- an anchor assembly including an expandable anchor frame defining an interior space and defining a plurality of sub-annular anchor feet, wherein the anchor assembly is expandable from a compressed anchor delivery configuration to an expanded anchor deployment configuration in which the sub-annular anchor feet are sized and shaped to engage along an underside of a mitral valve annulus;
- and
- a valve assembly including an expandable valve frame that is separately expandable from the expandable anchor frame and being nested within the interior space of the expandable anchor frame while the anchor assembly is in the compressed anchor delivery configuration, wherein the expandable valve frame defines a central orifice and a leaflet occluder positioned within the central orifice, wherein the valve assembly is expandable from a compressed valve delivery configuration to an expanded valve deployment configuration after the anchor assembly is in the expanded anchor deployment configuration.
Dependencies are inferred from the claim text.