Device and method for measuring metabolic rate using sequential gas delivery
AssigneeThornhill Scientific Inc.
InventorsJoseph Arnold FISHER, James DUFFIN, Olivia SOBCZYK, Bryan Drew MILLER, Rafay KHAN
Life of this patent
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Abstract
The present disclosure provides a device and method for measuring metabolic rate using sequential gas delivery. By delivering a first gas with a known quantity of gas X and a volume smaller than the subject's alveolar volume, and subsequently delivering a second gas to the subject, the metabolic rate can be accurately and precisely determined. The device measures an exhaled partial pressure of gas X and computes the metabolic rate based on the inhaled partial pressure of gas X, the exhale partial pressure of gas X, and the volume of the first gas.
Claims19
A method of measuring a subject's metabolic rate using sequential gas delivery, the method comprising:
- delivering a first gas over a first portion of the subject's inhalation, the first gas comprising an inhaled partial pressure of gas X, wherein the volume of the first gas is equal to or less than the subject's alveolar volume;
- delivering a second gas over a second portion of the subject's inhalation, the second gas comprising a partial pressure of gas X equal to an end-tidal partial pressure of gas X exhaled in a prior breath;
- measuring an exhaled partial pressure of gas X during the subject's exhalation;
- and
- computing the metabolic rate based on the inhaled partial pressure of gas X, the exhaled partial pressure of gas X, and the volume of the first gas.
A device for measuring a subject's metabolic rate comprising:
- a gas blender;
- and
- a processor connected to the gas blender;
- wherein the processor is configured to:
- control the gas blender to deliver a first gas over a first portion of the subject's inhalation, the first gas comprising an inhaled partial pressure of gas X, wherein the volume of the first gas is equal to or less than the subject's alveolar volume;
- control the gas blender to deliver a second gas over a second portion of the subject's inhalation, the second gas comprising an end-tidal partial pressure of gas X equal to a partial pressure of gas X exhaled in a prior breath;
- receive from a sensor an exhaled partial pressure of gas X measured during the subject's exhalation;
- and
- compute the metabolic rate based on the inhaled partial pressure of gas X, the exhaled partial pressure of gas X, and the volume of the first gas.
Dependencies are inferred from the claim text.