Pressure based structural heart assessment systems and methods
AssigneeOpsens Inc.
InventorsSébastien Lalancette, Thomas Goodhart, Maxime Picard Deland, Claude Belleville
Life of this patent
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Abstract
The heart valve assessment systems described herein advantageously provide indicators of a heart valve condition, such as a pressure gradient or a valve regurgitation index. The heart valve assessment systems can provide indicators of a heart valve condition during a heart procedure. A pressure gradient indicates a severity or measurement of the narrowing (or stenosis) of a valve by the increase in pressure behind it. A valve regurgitation index indicates a leakiness measurement of a valve.
Claims21
(canceled)
A system comprising:
- a non-transitory computer storage medium configured to at least store computer-executable instructions;
- and
- one or more hardware processors in communication with the non-transitory computer storage medium, the one or more hardware processors configured to execute the computer-executable instructions to at least:
- calibrate a second pressure sensor relative to a first pressure sensor while both sensors are positioned in a heart, wherein to calibrate the second pressure sensor relative to the first pressure sensor further comprises:
- determine a first plurality of pressure values from the first pressure sensor positioned in a first portion of the heart;
- determine a second plurality of pressure values from the second pressure sensor in a cardiovascular region adjacent to the first portion of the heart;
- detect a value at a substantially beginning of a systolic phase in the first plurality of pressure values;
- and
- calculate a time adjustment to the second plurality of pressure values such that a value from the second plurality of pressure values corresponds to the value at the substantially beginning of the systolic phase in the first plurality of pressure values;
- determine a third plurality of pressure values from the first pressure sensor positioned in the first portion of the heart;
- determine a fourth plurality of pressure values from the second pressure sensor positioned in the cardiovascular region adjacent to the first portion of the heart, wherein to determine the fourth plurality of pressure values further comprises:
- apply the time adjustment to an initial plurality of pressure values;
- detect a first feature in the third plurality of pressure values;
- detect a second feature in the fourth plurality of pressure values;
- determine a heart valve condition based at least in part on the first feature and the second feature;
- and
- display the heart valve condition on a user interface.
A method comprising:
- calibrating a second pressure sensor relative to a first pressure sensor while both sensors are positioned in a heart, wherein to calibrate the second pressure sensor relative to the first pressure sensor further comprises:
- determining a first plurality of pressure values from the first pressure sensor positioned in a first portion of the heart;
- determining a second plurality of pressure values from the second pressure sensor in a cardiovascular region adjacent to the first portion of the heart;
- detecting a value at a substantially beginning of a systolic phase in the first plurality of pressure values;
- calculating a time adjustment to the second plurality of pressure values such that a value from the second plurality of pressure values corresponds to the value at the substantially beginning of the systolic phase in the first plurality of pressure values;
- determining a third plurality of pressure values from the first pressure sensor positioned in the first portion of the heart;
- determining a fourth plurality of pressure values from the second pressure sensor positioned in the cardiovascular region adjacent to the first portion of the heart, wherein to determine the fourth plurality of pressure values further comprises:
- applying the time adjustment to an initial plurality of pressure values;
- detecting a first feature in the third plurality of pressure values;
- detecting a second feature in the fourth plurality of pressure values;
- determining a heart valve condition based at least in part on the first feature and the second feature;
- and
- displaying the heart valve condition on a user interface.
A system comprising:
- a non-transitory computer storage medium configured to at least store computer-executable instructions;
- and
- one or more hardware processors in communication with the non-transitory computer storage medium, the one or more hardware processors configured to execute the computer-executable instructions to at least:
- calibrate a second pressure sensor relative to a first pressure sensor while both sensors are positioned in a heart, wherein to calibrate the second pressure sensor relative to the first pressure sensor further comprises:
- determine a first plurality of pressure values from the first pressure sensor positioned in a first portion of the heart;
- determine a second plurality of pressure values from the second pressure sensor in a cardiovascular region adjacent to the first portion of the heart;
- detect a value at a substantially beginning of a systolic phase in the first plurality of pressure values;
- and
- calculate a time adjustment to the second plurality of pressure values such that a value from the second plurality of pressure values corresponds to the value at the substantially beginning of the systolic phase in the first plurality of pressure values;
- determine a third plurality of pressure values from the first pressure sensor positioned in the first portion of the heart;
- determine a fourth plurality of pressure values from the second pressure sensor positioned in the cardiovascular region adjacent to the first portion of the heart, wherein to determine the fourth plurality of pressure values further comprises:
- apply the time adjustment to an initial plurality of pressure values;
- and
- present a first user interface comprising:
- a first graph based at least in part on the third plurality of pressure values;
- and
- a second graph based at least in part on the fourth plurality of pressure values.
Dependencies are inferred from the claim text.