Methods for selecting a microbial strain for increased isoprenol production using an isoprenol biosensor

Abstract

The present invention provides for a method for increasing the production of a short chain alcohol, such as isoprenol or a diol, comprising: (a) providing a microbial strain comprising a genetic circuit comprising a short chain alcohol biosensor which allows growth of the microbial strain only when the microbial strain produces the short chain alcohol is produced, (b) screening for a cell with increased short chain alcohol production, and (c) optionally culturing or growing the cell to produce the short chain alcohol.

Dependencies are inferred from the claim text.