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US 2026/0250679 A1Published application
Methods and Compositions for Treatment of Polycystic Kidney Disease
AssigneeRegulus Therapeutics Inc.
InventorsDenis Drygin, Garth A. Kinberger, Edmund Chun Yu Lee
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Abstract
Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
Claims13
1-105. (canceled)
A method of treating polycystic kidney disease comprising administering to a human subject in need thereof a therapeutically effective amount of a modified oligonucleotide having the structure:
- or a pharmaceutically acceptable salt thereof, wherein the polycystic kidney disease is autosomal dominant polycystic kidney disease.
A method of treating polycystic kidney disease comprising administering to a human subject in need thereof a therapeutically effective amount of a modified oligonucleotide having the structure:
- wherein the polycystic kidney disease is autosomal dominant polycystic kidney disease.
Dependencies are inferred from the claim text.