Cnx antigen-binding molecules
AssigneesAgency for Science, Technology and Research, Albatroz Therapeutics Pte. Ltd.
InventorsFrederic Bard, Cheng-I Wang, Zhi Hui Joanne Chia, Eve Ngoh, Xavier Le Guezennec, Tham Keit Min, Anh Tuan Nguyen, Rebecca Bennion
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Abstract
Antigen binding molecules capable of binding to calnexin (CNX) are disclosed herein. Also disclosed are chimeric antigen receptors, antibody-drug conjugates, and compositions comprising such antigen binding molecules, as well as nucleic acids, vectors and cells. Uses and methods involving antigen binding molecules capable of binding to calnexin (CNX) are also disclosed.
Claims27
An antigen-binding molecule, optionally isolated, which binds to CNX.
The antigen-binding molecule according to any one of claims 1 to 8, wherein the antigen-binding molecule is a multispecific antigen-binding molecule, and wherein the antigen-binding molecule further comprises an antigen-binding domain which binds to an antigen other than CNX.
Dependencies are inferred from the claim text.