Polymer Composite Nanomaterial Encapsulation System
AssigneeCore Quantum Technologies, Inc.
InventorsKristie Marie Krug, Mythreyi Unni
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Abstract
Generally, a polymer nanomaterial encapsulation system useful in the production of polymer encapsulated nanoparticles comprised of a hydrophobic nanoparticle encapsulated in the hydrophobic region of the polymer with the external hydrophilic region of the polymer ensuring water-solubility and affording a functional group which can be utilized for the production of nanoparticle conjugates. Specifically, particular embodiments include a polymer nanoparticle structure including one or more of: a quantum dot and/or a superparamagnetic iron oxide nanoparticle and/or an upconverting nanoparticle, encapsulated in polystyrene-b-polyethylene glycol amine for the production of antibody conjugates useful in the capture of cellular targets.
Claims34
A nanocomposite, comprising:
- an amphiphile having a hydrophobic region and a hydrophilic region, said amphiphile comprises polystyrene-b-polyethylene glycol including a functional group, wherein said polystyrene-b-polyethylene glycol includes a polystyrene block and a polyethylene glycol block including a branched polyethylene glycol selected from the group of:
- a four arm polyethylene glycol, a six arm polyethylene glycol and an eight arm polyethylene glycol;
- and
- at least one nanoparticle encapsulated by association with said hydrophobic region of said amphiphile.
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Dependencies are inferred from the claim text.