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US 2026/0248948 A1Published application
Cytotoxic imidazo[1,2-a]pyridine compounds and their use in therapy
AssigneesMyricX Pharma Limited, Imperial College Innovations Limited
InventorsRobin CARR, Roberto SOLARI, Andrew Simon BELL, Edward William TATE, Roger BONNERT
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Abstract
The present invention relates to compounds of formula (I) and related aspects.
Claims29
-79. (canceled)
A compound of formula (I):
- wherein:
- R1 is a group of formula O-L-A;
- L is —(CH R12)m—;
- each R12 is H;
- m is 2;
- A is:
- v is 0;
- R9c is methyl, iso-propyl or tert-butyl;
- R9d is H or methyl;
- R10 is methyl;
- R11 is methyl;
- s is 1 or 2;
- each R2 is independently F, Cl, or Br;
- Y is CH;
- R3 is H;
- R4 is H;
- R5 is H or C1-4alkyl;
- R6 is H or C1-4alkyl;
- q is 0;
- or a salt and/or solvate thereof.
17 more elements
Dependencies are inferred from the claim text.