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US 2026/0248795 A1Published application
Methods for treating testicular and ovarian adrenal rest tumors
AssigneeSpruce Biosciences, Inc.
InventorsAlexis HOWERTON, Hal GERBER
Life of this patent
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Abstract
Provided herein are compounds and pharmaceutical compositions for the prevention and treatment of testicular adrenal rest tumors (TART) or ovarian adrenal rest tumors (OART).
Claims16
A method of treating a disease or disorder associated with excessive or deficient production of sex steroids in a subject, comprising administering to the subject a small molecule corticotropin-releasing factor type-1 (CRF1) antagonist, or a pharmaceutically acceptable salt thereof, wherein the small molecule CRF1 antagonist is:
- or a pharmaceutically acceptable salt thereof,
- wherein the subject is on a regimen of a glucocorticoid,
- wherein the subject is in a fed state.
Dependencies are inferred from the claim text.