Dexmedetomidine-containing transdermal patch and preparation method thereof
AssigneeBeijing Tide Pharmaceutical Co., Ltd.
InventorsJianteng PAN, Shaopeng ZHONG, Yun WU, Pingping ZHANG, Zhiyang YUE, Lei LIU, Leling GAN
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Abstract
The present application relates to the field of pharmaceutical biotechnology, and specifically relates to a dexmedetomidine-containing transdermal patch. By adding a penetration enhancer, the transdermal rate and transdermal amount are increased, and the onset time is shortened; the patch content is reduced, the residual amount in the skin is lowered, and skin redness/scarring at the administration site caused by drug accumulation in the skin is effectively avoided.
Claims20
A dexmedetomidine-containing transdermal patch, wherein the transdermal patch comprises a penetration enhancer, and the penetration enhancer is selected from the group consisting of dimethyl sulfoxide, azone, isopropyl palmitate, isopropyl myristate, oleic acid, ethyl oleate, oleyl alcohol, propylene glycol, polyglyceryl oleate, diethylene glycol monoethyl ether, eucalyptol, menthol and combinations of two or more thereof.
Dependencies are inferred from the claim text.