Compositions and methods for treating metabolic diseases/disorders
OwnerAchraf Noureddine, Charles Jeffrey Brinker +2inventors
InventorsAchraf Noureddine, Charles Jeffrey Brinker, Eric Brey, Maria A. Gonzalez Porras
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Abstract
Provided herein is a population of protocells comprising a lipid bi- or multi-layer, mesoporous silica nanoparticles (MSNPs), a cargo, and optionally a targeting ligand and methods of using the same.
Claims28
A population of protocells comprising a lipid bi- or multi-layer, mesoporous silica nanoparticles (MSNPs), a cargo, and an integrin alpha 7 (ITA7) targeting ligand.
A population of protocells comprising a lipid bi- or multi-layer, mesoporous silica nanoparticles (MSNPs) and a cargo, wherein the cargo comprises at least one of forskolin, 3-AR agonist CL-316243, rosiglitazone (Rosi) or GW0742 or peptides, proteins, antibodies, nucleic acids, or drugs that inhibit ITA7.
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Dependencies are inferred from the claim text.