A method for operating an intraocular drug administration device including an agent reservoir that is attached to an eyeball of an organism and has an outer cylinder portion holding an agent in a state of being in contact with the eyeball, a first electrode that is provided in the outer cylinder portion so as to be separated from the eyeball and cover at least a part of the eyeball, and is curved so as to be recessed in a direction away from the eyeball, a second electrode that can be energized between the first electrode and the second electrode, a power supply that supplies a current between the first electrode and the second electrode, a control device that controls the power supply, and a storage unit that stores a command to be executed by the control device, the method comprising:
- a first step, performed by the control device, of controlling the power supply to apply a high-voltage pulse between the first electrode and the second electrode a plurality of times.