Plication systems, plication/spring systems, and methods of use thereof

A plicator and spring system comprising:

• a first plicator system comprising:
• a first outer component including a first lumen, a first notch, and a retention mechanism;
• and
• a first inner component including a second lumen, a second notch, and a plurality of projections extending from an outer surface of the inner component, each of the plurality of extensions being arranged and configured to engage with the retention mechanism,
• wherein a portion of the inner component is disposed within the outer component so that the first lumen aligns with the second lumen, thereby generating a central lumen for the plicator system,
• wherein the first notch and the second notch are arranged and configured to form a first window with an open area into which a portion of tubular organ tissue may be invaginated when the plicator system is implanted into the tubular organ and the plicator system is arranged in an open configuration,
• wherein the plicator system is configured to translate from the open configuration to a closed configuration as the first inner component is pushed toward outer component, thereby reducing a size of the open area of the first window and clamping the invaginated tubular organ tissue therein so that the plicator system is securely implanted within the tubular organ;
• a second plicator system comprising:
• a second outer component including a third lumen, a third notch, and a retention mechanism;
• and
• a second inner component including a fourth lumen, a fourth notch, and a plurality of projections extending from an outer surface of the second inner component, each of the plurality of extensions being arranged and configured to engage with the retention mechanism,
• wherein a portion of the second inner component is disposed within the second outer component so that the third lumen aligns with the fourth lumen, thereby generating a central lumen for the second plicator system,
• wherein the first notch and the second notch are arranged and configured to form a second window with an open area into which a portion of tubular organ tissue may be invaginated when the plicator system is implanted into the tubular organ and the plicator system is arranged in an open configuration,
• wherein the plicator system is configured to translate from the open configuration to a closed configuration as the second inner component is pushed toward outer component, thereby reducing a size of the open area of the second window and clamping the invaginated tubular organ tissue therein so that the plicator system is securely implanted within the tubular organ;
• and
• a spring having a tubular body with a lumen therethrough that aligns with the first, second, third, and fourth lumen, the spring being attached to the first outer component and the second outer component and disposed therebetween.

A method for implanting a plicator and spring system into a tubular organ of a subject, the method comprising:

• positioning the plicator and spring system within the tubular organ;
• applying negative pressure to the plicator and spring system, thereby pulling tubular organ tissue into a window of the plicator and spring system;
• and
• actuating the plicator and spring system to secure the tubular organ tissue within the window.