Flexible biosensor for the detection and/or 2d/3d mapping of biomarker concentration

Abstract

Disclosed are biosensors for detecting an analyte of interest. These biosensors can comprise one or more electrochemical sensors disposed on a flexible substrate. Each of the one or more electrochemical sensors can comprise a first electrode disposed on a flexible substrate; a second electrode disposed on the flexible substrate and in electrochemical contact with the first electrode; and an active layer comprising an enzyme disposed on the first electrode. The biosensor can exploit the fact that many co-substrates or products of the reaction catalyzed by the enzyme are electroactive and/or that reaction of the enzyme with the analyte of interest can involve a redox process that can generate an electronic current in proportion to the concentration of the analyte of interest. These biosensors can thus be used to measure the concentration of an analyte of interest in contact with the active layer by measuring sensor current and/or potential.

Dependencies are inferred from the claim text.